[Sg] - Singaporeans eagerly await the arrival of Moderna's 2-in-1 combo vaccine for Covid & Influenza to get vaccinated asap

[porcaputtana]

pics from healthhub lah. wanna kay siao. knn think ppl stupid like u?

Yes I do

Hand to heart and with every sincerity

I think your are really really stupid

 

[dredd]

Still talking about COVID vaccine? That ship has sailed long ago. 98% of us are happily vaccinated, having fulfilling lives leaving these 2% of low SES science deniers here miserable and bitching everyday about people trying to kill them.

Meanwhile in the world of science, mRNA is forging ahead with other breakthroughs, something these 2% of morons here can never wrap their small brains around.

More Than COVID-19: 6 Other Promising mRNA Vaccines in the Pipeline​

Written by Alyssa Billingsley, PharmD | Reviewed by Christina Aungst, PharmD

Key takeaways:

• Companies are studying the technology behind the Pfizer and Moderna COVID-19 vaccines for other uses. This includes HIV, the flu, and even cancer.
• Many of these vaccines are just getting started in human clinical trials. That means researchers are still figuring out the best dose and if they’ll potentially work.
• There are currently cytomegalovirus (CMV), influenza (flu), and respiratory syncytial virus (RSV) mRNA vaccines in phase 3 clinical trials.

Anna Ohanesian/iStock via Getty Images
In December 2020, the Pfizer and Moderna COVID-19 vaccines became the first messenger RNA (mRNA) vaccines to be authorized by the FDA. The technology behind the vaccines had been studied for over 30 years. But this was the first time it became available to the public. Fast forward to today, and both vaccines are fully FDA approved.
Now, companies are starting to study mRNA vaccines for other potential uses. This includes infections like HIV and cytomegalovirus (CMV), for which vaccine development has been an ongoing feat.

What is mRNA vaccine technology and how does it work?​

Messenger RNA (mRNA) vaccines work differently compared to other vaccines. For example, other vaccines may contain weakened or dead germs (or part of the germ). This trains your immune system to quickly recognize and fight the germ if you’re exposed to it in the future.
But mRNA vaccines don’t contain germs at all. Instead, they contain something called mRNA. Your body has its own mRNA inside of cells. Think of mRNA as a set of instructions. Your cells use these instructions to make proteins that your body needs. But the mRNA in vaccines can also be used to instruct your cells to make certain proteins, too.
For example, the vaccine mRNA might contain the code to make part of a germ (called an antigen). When delivered to your cells, it instructs your cells to make the antigen. This is what triggers your immune system to respond to an mRNA vaccine.

In the case of the COVID vaccines, your cells are instructed to make part of SARS-CoV-2 (the virus that causes COVID). This is what triggers your immune system and creates protection against the virus if you encounter it in the future.
Delivering instructions to make part of a germ is just one way that mRNA vaccines can work. Another example is how mRNA cancer vaccines work. They help your immune system recognize and target proteins or mutations found on certain cancer cells. In other words, there are many different ways to use this technology. More on that below.

What other mRNA vaccines are currently being researched?​

With the success of the mRNA COVID vaccines, it makes sense that companies would explore mRNA technology for other uses. Below are six examples.

1. Influenza (flu)​

Flu vaccine effectiveness is estimated to be between 40% and 60%. But this is when flu virus strains in the vaccine are closely matched to those circulating in the population. An mRNA flu vaccine may have the potential to improve upon current flu vaccines. In fact, companies were working on them before COVID.
At least four mRNA flu vaccines have started clinical trials, including:

• National Institute of Allergy and Infectious Disease (NIAID): In May 2023, NIAID started enrolling participants in a phase 1 trial studying a universal flu vaccine that uses mRNA technology. A universal vaccine would cover many different strains, ideally for a longer period of time. This could lessen the need for annual flu shots.
• Sanofi: In 2021, Sanofi announced positive findings from a phase 1/2 clinical trial studying an mRNA flu vaccine that targets one strain of the flu virus. Since then, it has launched a phase 1/2 trial for a vaccine targeting four different strains.
• Pfizer: In September 2022, Pfizer announced the launch of a phase 3 clinical trial for a single-dose mRNA flu vaccine for adults that targets four strains of the flu virus. The trial is expected to be completed in 2024.
• Moderna: Moderna currently has five mRNA flu vaccines in clinical trials. One vaccine is in phase 3 trials and has been recently updated to work better against influenza B strains of the virus.

In addition to a seasonal flu vaccine, Moderna is also researching a combination mRNA COVID and flu vaccine, as well as one that also protects against respiratory syncytial virus (RSV). This could be a more convenient option if COVID booster shots are recommended every year, like flu shots. Moderna expects combination vaccines to be available by 2025.

2. Zika virus​

A Zika virus infection can be especially risky for some people. This includes pregnant women, since it can cause stillbirth, miscarriage, and birth defects in an unborn baby. To date, there are no vaccines or treatments for a Zika virus infection.
There are several different Zika virus vaccines in development. But Moderna is studying the only one that uses mRNA. The company is currently studying the vaccine in a phase 2 clinical trial involving adults ages 18 to 65. The study is expected to be completed in 2024.

3. Respiratory syncytial virus (RSV)​

Respiratory syncytial virus (RSV) is a respiratory virus. For many people, an RSV infection doesn’t result in serious illness. But it can be dangerous for certain people, like older adults and babies.
After unsuccessful prior attempts to develop a safe and effective RSV, there are now two FDA-approved RSV vaccines for older adults: Arexvy and Abrysvo. Both are considered protein subunit vaccines. This is similar to how the Novavax COVID vaccine works.
Moderna is currently studying an mRNA RSV vaccine for adults ages 60 and older in a phase 2/3 clinical trial. The company anticipates applying for approval during 2023. An mRNA RSV vaccine, as well as a combination vaccine targeting RSV and human metapneumovirus, is also being studied in a phase 1 trial that includes children under 24 months old.

4. HIV​

HIV was first identified as the cause of AIDS in 1984. Since then, there have been many attempts to develop an effective HIV vaccine. But so far, none have been successful. There are several factors that make HIV vaccine development challenging. For example, the virus mutates frequently. Vaccines would need to keep up with these changes in order to work.
Moderna has mRNA HIV vaccines going through three phase 1 clinical trials. The company hopes to identify a viable vaccine candidate to move forward to phase 2 trials.
NIAID also has an mRNA HIV vaccine in a phase 1 clinical trial. The trial is expected to be complete in October 2023.

5. Cytomegalovirus (CMV)​

Cytomegalovirus (CMV) is a common virus that can cause serious symptoms in people with weakened immune systems. Babies can also be born with a CMV infection, which can result in hearing loss. This is called a congenital CMV infection. Currently, there’s no CMV vaccine available.
Moderna is currently studying an mRNA CMV vaccine in a phase 3 clinical trial that includes women ages 16 to 40 years old. The trial is expected to be completed in 2026.
Moderna is studying the vaccine in this group because the virus can be transmitted from an infected mother to an unborn baby during pregnancy. This can result in a congenital CMV infection, which can cause vision problems, hearing loss, and other health issues.

6. Cancer​

When you think of vaccines, preventing an infection likely comes to mind. You may be surprised to learn that there are cancer vaccines, too. But they’re used to treat cancer, not prevent it. Cancer vaccines work by helping your immune system find and destroy cancer cells.
Cancer mRNA vaccines are being studied alone and in combination with other cancer treatments, like chemotherapy and immunotherapy. Immunotherapy helps your immune system find and kill cancer cells.
There are several mRNA cancer vaccines in clinical trials. Some of them are personalized cancer vaccines. This means they’re made just for you based on your tumor sample. Others aren’t personalized. They work by helping your immune system target proteins found on cancer cells.

• Moderna is studying at least three cancer vaccines in clinical trials. One is considered to be a personalized cancer vaccine. It’s currently in a phase 2 trial and treats melanoma. Another vaccine is in a phase 1 trial and treats solid tumors. The third vaccine is also in a phase 1 trial that was completed in August 2022. It targets a specific cancer cell protein in non-small cell lung cancer (NSCLC), colorectal cancer, and pancreatic cancer.
• Memorial Sloan Kettering Cancer Center is studying an mRNA cancer vaccine for pancreatic cancer. Due to promising phase 1 trial results, researchers expect to start enrolling participants in a larger clinical trial in summer 2023.
• The University Medical Center Groningen is collaborating with BioNTech on an mRNA cancer vaccine for ovarian cancer. The vaccine is currently in a phase 1 clinical trial, and it’s being studied in combination with chemotherapy.
• BioNTech is also collaborating with Regeneron Pharmaceuticals on an mRNA cancer vaccine for advanced melanoma. It’s currently in phase 2 clinical trials. The study is expected to be completed in 2025.

The bottom line​

The COVID-19 vaccines have shown that mRNA technology can be effective in vaccines. Because of this, companies are testing it for many other applications. In some cases, they may even offer hope where other vaccines have been unsuccessful, like with HIV.
Most of the mRNA vaccines being studied are in phase 1 clinical trials, with a few in phase 2 and 3 trials. So, there’s more research to be done until we know how well they’ll work in preventing infections or treating cancer. If they’re shown to be safe and effective, we may see more of them hit the market over the next several years.

 

[hbk75]

Yes I do

Hand to heart and with every sincerity

I think your are really really stupid

still i think u are a stupid person full of shit inside the brain. in your mind thinking mrna is god like mode but other hand dun dare to take the jabs. LOL

 

[mojito]

Me two years never jab, two years never get covid, two years never get sick, never get mc.

Amazing! Safe and effective vaxxing upskill ur macrophages to beat new viruses.

 

[Loofydralb]

By uneducated idiots like you ?

I am sure I am losing sleep over it

Yes you're losing sleep. You're posting at 3.30am.

You may think you're educated but you're just a good memorizer and regurgitator.

Ok Let's compare that to an
Educated idiot SUPERCUCK like you who cannot even smell the mRNA scam, run by lying big pharmas, when literally put in front of your own nose.

Frankly education is useless on people like you.

 

[porcaputtana]

still i think u are a stupid person full of shit inside the brain.

I know what is mRNA

Do you ?

 

[porcaputtana]

You may think you're educated but you're just a good memorizer and regurgitator.

Ok Let's compare that to an
Educated idiot SUPERCUCK like you who cannot even smell the mRNA scam, run by lying big pharmas, when literally put in front of your own nose.

Frankly education is useless on people like you.

Proper education brought me to a status where I can employ mats to do my garden and wash my cars

All in all I’d say it’s a good thing

 

[Loofydralb]

Proper education ....

HAHAHAHAHA

Properly failed to educate you to spot a scam.
Properly failed to be educated to have a spine.

 

[Leongsam]

Still talking about COVID vaccine? That ship has sailed long ago. 98% of us are happily vaccinated, having fulfilling lives leaving these 2% of low SES science deniers here miserable and bitching everyday about people trying to kill them.

Meanwhile in the world of science, mRNA is forging ahead with other breakthroughs, something these 2% of morons here can never wrap their small brains around.

More Than COVID-19: 6 Other Promising mRNA Vaccines in the Pipeline​

Written by Alyssa Billingsley, PharmD | Reviewed by Christina Aungst, PharmD

Key takeaways:

• Companies are studying the technology behind the Pfizer and Moderna COVID-19 vaccines for other uses. This includes HIV, the flu, and even cancer.
• Many of these vaccines are just getting started in human clinical trials. That means researchers are still figuring out the best dose and if they’ll potentially work.
• There are currently cytomegalovirus (CMV), influenza (flu), and respiratory syncytial virus (RSV) mRNA vaccines in phase 3 clinical trials.

Anna Ohanesian/iStock via Getty Images
In December 2020, the Pfizer and Moderna COVID-19 vaccines became the first messenger RNA (mRNA) vaccines to be authorized by the FDA. The technology behind the vaccines had been studied for over 30 years. But this was the first time it became available to the public. Fast forward to today, and both vaccines are fully FDA approved.
Now, companies are starting to study mRNA vaccines for other potential uses. This includes infections like HIV and cytomegalovirus (CMV), for which vaccine development has been an ongoing feat.

What is mRNA vaccine technology and how does it work?​

Messenger RNA (mRNA) vaccines work differently compared to other vaccines. For example, other vaccines may contain weakened or dead germs (or part of the germ). This trains your immune system to quickly recognize and fight the germ if you’re exposed to it in the future.
But mRNA vaccines don’t contain germs at all. Instead, they contain something called mRNA. Your body has its own mRNA inside of cells. Think of mRNA as a set of instructions. Your cells use these instructions to make proteins that your body needs. But the mRNA in vaccines can also be used to instruct your cells to make certain proteins, too.
For example, the vaccine mRNA might contain the code to make part of a germ (called an antigen). When delivered to your cells, it instructs your cells to make the antigen. This is what triggers your immune system to respond to an mRNA vaccine.

In the case of the COVID vaccines, your cells are instructed to make part of SARS-CoV-2 (the virus that causes COVID). This is what triggers your immune system and creates protection against the virus if you encounter it in the future.
Delivering instructions to make part of a germ is just one way that mRNA vaccines can work. Another example is how mRNA cancer vaccines work. They help your immune system recognize and target proteins or mutations found on certain cancer cells. In other words, there are many different ways to use this technology. More on that below.

What other mRNA vaccines are currently being researched?​

With the success of the mRNA COVID vaccines, it makes sense that companies would explore mRNA technology for other uses. Below are six examples.

1. Influenza (flu)​

Flu vaccine effectiveness is estimated to be between 40% and 60%. But this is when flu virus strains in the vaccine are closely matched to those circulating in the population. An mRNA flu vaccine may have the potential to improve upon current flu vaccines. In fact, companies were working on them before COVID.
At least four mRNA flu vaccines have started clinical trials, including:

• National Institute of Allergy and Infectious Disease (NIAID): In May 2023, NIAID started enrolling participants in a phase 1 trial studying a universal flu vaccine that uses mRNA technology. A universal vaccine would cover many different strains, ideally for a longer period of time. This could lessen the need for annual flu shots.
• Sanofi: In 2021, Sanofi announced positive findings from a phase 1/2 clinical trial studying an mRNA flu vaccine that targets one strain of the flu virus. Since then, it has launched a phase 1/2 trial for a vaccine targeting four different strains.
• Pfizer: In September 2022, Pfizer announced the launch of a phase 3 clinical trial for a single-dose mRNA flu vaccine for adults that targets four strains of the flu virus. The trial is expected to be completed in 2024.
• Moderna: Moderna currently has five mRNA flu vaccines in clinical trials. One vaccine is in phase 3 trials and has been recently updated to work better against influenza B strains of the virus.

In addition to a seasonal flu vaccine, Moderna is also researching a combination mRNA COVID and flu vaccine, as well as one that also protects against respiratory syncytial virus (RSV). This could be a more convenient option if COVID booster shots are recommended every year, like flu shots. Moderna expects combination vaccines to be available by 2025.

2. Zika virus​

A Zika virus infection can be especially risky for some people. This includes pregnant women, since it can cause stillbirth, miscarriage, and birth defects in an unborn baby. To date, there are no vaccines or treatments for a Zika virus infection.
There are several different Zika virus vaccines in development. But Moderna is studying the only one that uses mRNA. The company is currently studying the vaccine in a phase 2 clinical trial involving adults ages 18 to 65. The study is expected to be completed in 2024.

3. Respiratory syncytial virus (RSV)​

Respiratory syncytial virus (RSV) is a respiratory virus. For many people, an RSV infection doesn’t result in serious illness. But it can be dangerous for certain people, like older adults and babies.
After unsuccessful prior attempts to develop a safe and effective RSV, there are now two FDA-approved RSV vaccines for older adults: Arexvy and Abrysvo. Both are considered protein subunit vaccines. This is similar to how the Novavax COVID vaccine works.
Moderna is currently studying an mRNA RSV vaccine for adults ages 60 and older in a phase 2/3 clinical trial. The company anticipates applying for approval during 2023. An mRNA RSV vaccine, as well as a combination vaccine targeting RSV and human metapneumovirus, is also being studied in a phase 1 trial that includes children under 24 months old.

4. HIV​

HIV was first identified as the cause of AIDS in 1984. Since then, there have been many attempts to develop an effective HIV vaccine. But so far, none have been successful. There are several factors that make HIV vaccine development challenging. For example, the virus mutates frequently. Vaccines would need to keep up with these changes in order to work.
Moderna has mRNA HIV vaccines going through three phase 1 clinical trials. The company hopes to identify a viable vaccine candidate to move forward to phase 2 trials.
NIAID also has an mRNA HIV vaccine in a phase 1 clinical trial. The trial is expected to be complete in October 2023.

5. Cytomegalovirus (CMV)​

Cytomegalovirus (CMV) is a common virus that can cause serious symptoms in people with weakened immune systems. Babies can also be born with a CMV infection, which can result in hearing loss. This is called a congenital CMV infection. Currently, there’s no CMV vaccine available.
Moderna is currently studying an mRNA CMV vaccine in a phase 3 clinical trial that includes women ages 16 to 40 years old. The trial is expected to be completed in 2026.
Moderna is studying the vaccine in this group because the virus can be transmitted from an infected mother to an unborn baby during pregnancy. This can result in a congenital CMV infection, which can cause vision problems, hearing loss, and other health issues.

6. Cancer​

When you think of vaccines, preventing an infection likely comes to mind. You may be surprised to learn that there are cancer vaccines, too. But they’re used to treat cancer, not prevent it. Cancer vaccines work by helping your immune system find and destroy cancer cells.
Cancer mRNA vaccines are being studied alone and in combination with other cancer treatments, like chemotherapy and immunotherapy. Immunotherapy helps your immune system find and kill cancer cells.
There are several mRNA cancer vaccines in clinical trials. Some of them are personalized cancer vaccines. This means they’re made just for you based on your tumor sample. Others aren’t personalized. They work by helping your immune system target proteins found on cancer cells.

• Moderna is studying at least three cancer vaccines in clinical trials. One is considered to be a personalized cancer vaccine. It’s currently in a phase 2 trial and treats melanoma. Another vaccine is in a phase 1 trial and treats solid tumors. The third vaccine is also in a phase 1 trial that was completed in August 2022. It targets a specific cancer cell protein in non-small cell lung cancer (NSCLC), colorectal cancer, and pancreatic cancer.
• Memorial Sloan Kettering Cancer Center is studying an mRNA cancer vaccine for pancreatic cancer. Due to promising phase 1 trial results, researchers expect to start enrolling participants in a larger clinical trial in summer 2023.
• The University Medical Center Groningen is collaborating with BioNTech on an mRNA cancer vaccine for ovarian cancer. The vaccine is currently in a phase 1 clinical trial, and it’s being studied in combination with chemotherapy.
• BioNTech is also collaborating with Regeneron Pharmaceuticals on an mRNA cancer vaccine for advanced melanoma. It’s currently in phase 2 clinical trials. The study is expected to be completed in 2025.

The bottom line​

The COVID-19 vaccines have shown that mRNA technology can be effective in vaccines. Because of this, companies are testing it for many other applications. In some cases, they may even offer hope where other vaccines have been unsuccessful, like with HIV.
Most of the mRNA vaccines being studied are in phase 1 clinical trials, with a few in phase 2 and 3 trials. So, there’s more research to be done until we know how well they’ll work in preventing infections or treating cancer. If they’re shown to be safe and effective, we may see more of them hit the market over the next several years.

I'm all for mRNA vaccines. The technology is a leap forward and using it cure diseases such as cancer and HIV would be a godsend.


As is the case with all treatments the risk of the treatment has to outweigh the risk of the disease it is supposed to treat. With cancer and HIV this is a no brainer.

However for a young, healthy individual Covid 19 poses less of a risk than the "vaccine" that does not prevent infection or transmission in the first place.

 

[dredd]

I'm all for mRNA vaccines. The technology is a leap forward and using it cure diseases such as cancer and HIV would be a godsend.


As is the case with all treatments the risk of the treatment has to outweigh the risk of the disease it is supposed to treat. With cancer and HIV this is a no brainer.

However for a young, healthy individual Covid 19 poses less of a risk than the "vaccine" that does not prevent infection or transmission in the first place.

That is a valid argument. However, to be fair, not much is known about COVID-19 when it first appeared and keeps mutating. One thing is clear though - scientific data shows vaccines to prevent bad outcomes of COVID-19, whatever age or risk group you are in.

The CTs the simpletons here keep perpetuating that all vaccinated people will die of heart or any other ways is factually false. We all know that patients with underlying diseases like cardiovascular diseases always have poor outcomes from getting COVID-19, even after recovering from it. And because almost all of us have caught COVID-19, the % of people dying from heart attacks will increase. So the real reason for this happening is COVID-19, not the vaccines. Myocardities and Pericarditis after vaccination remains rare. People who die from taking paracetamol (panadol) for a headache around the world is greater than people dying from cardiovascular disease after vaccination.

Just so you know...

 

[Leongsam]

The CTs the simpletons here keep perpetuating that all vaccinated people will die of heart or any other ways is factually false. We all know that patients with underlying diseases like cardiovascular diseases always have poor outcomes from getting COVID-19, even after recovering from it. And because almost all of us have caught COVID-19, the % of people dying from heart attacks will increase. So the real reason for this happening is COVID-19, not the vaccines. Myocardities and Pericarditis after vaccination remains rare. People who die from taking paracetamol (panadol) for a headache around the world is greater than people dying from cardiovascular disease after vaccination.

Just so you know...

This is where the controversy lies.

The establishment and people like yourself are claiming that the risk of complications from the vaccine are extremely low and catching Covid is far more risky.

However there are a significant numbers of medical professionals who claim that the risk of serious adverse effects from Covid mRNA vaccines is way higher than the risks posed by Covid as far as young healthy individuals are concerned.

They cannot both be right but as far as I can see the jury is out as it is very hard to prove that an adverse outcome was caused by the vaccine but very easy to say that "there is no evidence of causation" which is the obvious response from those with a vested interest in promoting vaccination ie governments and the pharma industry and those beholden to them.

My view is that since the vaccines do not prevent transmission they should not have been made a prerequisite for employment and social interaction.

 

[hbk75]

I know what is mRNA

Do you ?

U know but u dun dare to take. Really boh lampa

 

[dredd]

This is where the controversy lies.

The establishment and people like yourself are claiming that the risk of complications from the vaccine are extremely low and catching Covid is far more risky.

However there are a significant numbers of medical professionals who claim that the risk of serious adverse effects from Covid mRNA vaccines is way higher than the risks posed by Covid as far as young healthy individuals are concerned.

They cannot both be right but as far as I can see the jury is out as it is very hard to prove that an adverse outcome was caused by the vaccine but very easy to say that "there is no evidence of causation" which is the obvious response from those with a vested interest in promoting vaccination ie governments and the pharma industry and those beholden to them.

My view is that since the vaccines do not prevent transmission they should not have been made a prerequisite for employment and social interaction.

You are speaking from a position of conjecture and have not experienced real cases where people are actually in ICU gasping for air and dying so you won't know how COVID-19 kills.

Science is not based on medical opinions but on real data gathered and they don't lie. That is how we know vaccination saves lives. That is why people are encouraged to protect themselves wih vaccination. You can continue to believe in CTs about big pharma and whatever, but facts are still facts.

 

[Leongsam]

You are speaking from a position of conjecture and have not experienced real cases where people are actually in ICU gasping for air and dying so you won't know how COVID-19 kills.

Science is not based on medical opinions but on real data gathered and they don't lie. That is how we know vaccination saves lives. That is why people are encouraged to protect themselves wih vaccination. You can continue to believe in CTs about big pharma and whatever, but facts are still facts.

Many aspects of medical treatment have been based upon conventional wisdom not facts. Remember there was an era when blood letting was supposed to do wonders and leeches were a medical necessity? How about lobotomies how many people did this procedure help?

Wisdom changes with time thank goodness or we'd all be in big trouble.

And if you are so fixated on data why are you refusing to acknowledge that Singapore's CFR was lower before vaccinations were available and shot up once mass vaccination commenced?

On 31 Dec 2020 it was 0.05% when no vaccine was available.

On 31 Dec 2021 it was 0.3% when multiple doses had already been administered to vast numbers.

 

[porcaputtana]

And if you are so fixated on data why are you refusing to acknowledge that Singapore's CFR was lower before vaccinations were available and shot up once mass vaccination commenced?

On 31 Dec 2020 it was 0.05% when no vaccine was available.

On 31 Dec 2021 it was 0.3% when multiple doses had already been administered to vast numbers.

yet again a layperson gets fixated on one parameter (CFR) and then links it to another parameter (vaccination) and jumps to the wrong conclusion.

the wonders of a simple mind .

have you considered an increase in sample size (more people hit by Covid by Dec 2021) as a confounding factor in the higher CFR ?

or perhaps more cases reported because the diagnostic criteria is more accurate by then ?

or perhaps without vaccine protection the CFR would have been way much higher ?

based on the larger sample size have you considered whether your increase to 0.3% (assuming this number is correct) is even statistically significant (p value )?

and is your CFR a be all and end all to determine vaccine efficacy? What about IFR ?

Finally since you are such an expert on CFR: the final CFR by June 2023 was 0.08%. One of the lowest in the world . Why is that ? Med beds ?

Medical data interpretation and statistical analysis is complex and taught at the post grad level . Same as critical analysis of medical journals

Most of us are not experts even after a year of training . That’s why we hire medical statisticians to help us analyse data during research.

Stick to porn Sam. Stick to porn . Don’t play with medical facts and embarrass yourself again.


https://ourworldindata.org/mortality-risk-covid

https://www.who.int/news-room/commentaries/detail/estimating-mortality-from-covid-19

https://www.ncid.sg/News-Events/New...ses-results-in-more-deaths-from-COVID-19.aspx

https://www.moh.gov.sg/resources-st...-during-the-covid-19-pandemic-up-to-june-2022

https://en.wikipedia.org/wiki/COVID-19_pandemic_in_Singapore

 

[porcaputtana]

This is where the controversy lies.

The establishment and people like yourself are claiming that the risk of complications from the vaccine are extremely low and catching Covid is far more risky.

We don’t claim. The risk benefit ratio has been robustly demonstrated in multi center Meta analysis and accepted for publication in high impact journals like Nature and NEJM. You know how to google pubmed so look for them yourself .

However there are a significant numbers of medical professionals who claim that the risk of serious adverse effects from Covid mRNA vaccines is way higher than the risks posed by Covid as far as young healthy individuals are concerned.

Significant number of quacks. If you were a bit more inquisitive you’d look into the background of these medical professionals hawking rubbish . Most of them are not even MDs but homeopaths. If they were MD they would been stuck off like the original founder of the anti vaxx movement in the UK . These idiots are already anti establishment with an axe to grind . Anti vaxx doctors fabricate data with the intention to mislead and to serve their own agenda. Most illustrious is our very own Dr Jipson. Soon to be struck off and sent to jail. Goh Meng Seng’s laundry list of medical journals submitted to MOH recently also authored by the same bunch of charlatans .

https://en.wikipedia.org/wiki/Andrew_Wakefield

https://www.asiaone.com/singapore/e...ts-peoples-power-partys-call-suspend-covid-19

They cannot both be right but as far as I can see the jury is out as it is very hard to prove that an adverse outcome was caused by the vaccine but very easy to say that "there is no evidence of causation" which is the obvious response from those with a vested interest in promoting vaccination ie governments and the pharma industry and those beholden to them.

Very hard ? Your circus of morons here would attribute getting run over by a truck as death caused by vaccination.

My view is that since the vaccines do not prevent transmission they should not have been made a prerequisite for employment and social interaction.

You obviously have never managed a pandemic of a new virus . Go read up on herd immunity.

The mantra you keep droning on and on ad nauseum is since young people are at low risk from covid they should be left alone .

Assuming you are right and we did unnecessarily jab this cohort of the population: SO WHAT ?

With the risk of vaccine induced myocarditis at 0.0002 to 0.0011% I would say yes please inject every single young motherfucker so we can quickly achieve herd immunity and get the hell back to normalcy .

SARS-Covid 19 pandemic is over. Next pandemic will come . I eagerly look forward to hearing your armchair general wisdom again.

https://www.hsa.gov.sg/docs/default...no-15-on-covid-19-vaccines-(30-june-2023).pdf

 

[porcaputtana]

U know but u dun dare to take. Really boh lampa

Messenger RNA is transcribed from nucleus DNA and gives instructions to cellular ribosomes to produce proteins and enzymes to keep your body alive and in function.

This takes place every microsecond every day in every cell of your body.

This fact is taught at A Levels Biology.

So even in an ignorant low SES anti vaxxtard like you , there are already trillions of mRNA .

So why are you afraid of mRNA ?

 

[Leongsam]

yet again a layperson gets fixated on one parameter (CFR) and then links it to another parameter (vaccination) and jumps to the wrong conclusion.

the wonders of a simple mind .

have you considered an increase in sample size (more people hit by Covid by Dec 2021) as a confounding factor in the higher CFR ?

or perhaps more cases reported because the diagnostic criteria is more accurate by then ?

or perhaps without vaccine protection the CFR would have been way much higher ?

based on the larger sample size have you considered whether your increase to 0.3% (assuming this number is correct) is even statistically significant (p value )?

and is your CFR a be all and end all to determine vaccine efficacy? What about IFR ?

Finally since you are such an expert on CFR: the final CFR by June 2023 was 0.08%. One of the lowest in the world . Why is that ? Med beds ?

Medical data interpretation and statistical analysis is complex and taught at the post grad level . Same as critical analysis of medical journals

Most of us are not experts even after a year of training . That’s why we hire medical statisticians to help us analyse data during research.

Stick to porn Sam. Stick to porn . Don’t play with medical facts and embarrass yourself again.


https://ourworldindata.org/mortality-risk-covid

https://www.who.int/news-room/commentaries/detail/estimating-mortality-from-covid-19

https://www.ncid.sg/News-Events/New...ses-results-in-more-deaths-from-COVID-19.aspx

https://www.moh.gov.sg/resources-st...-during-the-covid-19-pandemic-up-to-june-2022

https://en.wikipedia.org/wiki/COVID-19_pandemic_in_Singapore

I was waiting for you to come up with the correct interpretation of the CFR figures. You have failed miserably. It is not about sample sizes or diagnostic criteria.

I will give you a hint...... what was the main difference between those that caught Covid in 2020 vs 2021 onwards. Therein lies the answer.

The 4 boards that certified you obviously did not do a very thorough job.

 

[porcaputtana]

I was waiting for you to come up with the correct interpretation of the CFR figures. You have failed miserably. It is not about sample sizes or diagnostic criteria.

I will give you a hint...... what was the main difference between those that caught Covid in 2020 vs 2021 onwards. Therein lies the answer.

The 4 boards that certified you obviously did not do a very thorough job.

Of course

Show me how you calculate and reach your conclusion

Right here

I'll show it to my resident statistician and see if he pushes out a hernia laughing

The wonders of a simple mind

 

[dredd]

I was waiting for you to come up with the correct interpretation of the CFR figures. You have failed miserably. It is not about sample sizes or diagnostic criteria.

I will give you a hint...... what was the main difference between those that caught Covid in 2020 vs 2021 onwards. Therein lies the answer.

The 4 boards that certified you obviously did not do a very thorough job.

Your understanding of CFR is as flawed as the way you view statistics. No need for hints. You should stick to porn instead of talking medical because your postings show you know fark-all about science.