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[COVID-19 Virus] The Sinkies are fucked Thread.

endemic strategy
good luck to sinkypura


Covid variant first detected in South Africa 'most mutated so far' variant found so far

A South African Covid variant "could be more infectious" than other mutations and may have the potential to evade vaccines, scientists warn.

The C.1.2 strain was first identified by scientists in South Africa in May and has since been found in England, China, the Democratic Republic of the Congo, Mauritius, New Zealand, Portugal and Switzerland.

The strain has been linked to 'increased transmissibility' and now said to be more mutations away from the original virus which was first seen in Wuhan, China.

According to experts at South Africa's National Institute for Communicable Diseases and the KwaZulu-Natal Research Innovation and Sequencing Platform, the C.1.2 strain has a mutation rate of about 41.8 mutations per year.

This is nearly double the current global mutation rate seen in any other Variant of Concern (VOC) to date.

Researchers discovered a monthly increase in the number of C.1.2 genomes in South Africa, rising from 0.2 per cent in May to 1.6 per cent in June and 2.0 per cent in July.

The Alpha, Beta and Gamma variants have also shown a short period of consistent increase.

Scientists also found 14 mutations in nearly 50 per cent of the variants which had a C.1.2 sequence.

While more research is needed 'to determine the functional impact of these mutations', scientists have warned that the latest variant, which has 'mutated substantially', could help the virus evade antibodies and immune responses

In the report, which was published in the journal Nature, the scientists said: "We describe and characterise a newly identified SARS-CoV-2 lineage with several spike mutations that is likely to have emerged in a major metropolitan area in South Africa after the first wave of the epidemic, and then to have spread to multiple locations within two neighbouring provinces.

"We show that this lineage has rapidly expanded and become dominant in three provinces, at the same time as there has been a rapid resurgence in infections.

"Although the full import of the mutations is not yet clear, the genomic and epidemiological data suggest that this variant has a selective advantage—from increased transmissibility, immune escape or both.

"These data highlight the urgent need to refocus the public health response in South Africa on driving transmission down to low levels, not only to reduce hospitalisations and deaths but also to limit the spread of this lineage and the further evolution of the virus."

Public Health England published a report earlier this month which revealed that the C.1.2 strain was among 10 variants being monitored by scientists in the UK.

In April, scientists found another South African strain — called B.1.351 — had the potential to 'break through' the Pfizer jab.

The study compared almost 400 people who had tested positive for Covid-19, 14 days or more after they received one or two doses of the vaccine, against the same number of unvaccinated patients with the disease.

The Pfizer vaccine appeared to be less effective against the South African variant, researchers said, and has the ability to 'evade' protection.
 
sinkypura bus interchanges and public buses gone case liao. those taking buses..beware! better wear ppe gear when taking buses



As of Sunday, seven bus interchanges across Singapore have been identified as active coronavirus clusters, with a combined 174 cases.

The affected interchanges are located in Jurong East, Clementi, Punggol, Toa Payoh, Bishan, Sengkang and Boon Lay.


Read more at https://www.todayonline.com/singapore/120-bus-drivers-7-interchanges-infected-covid-19-lta
 
30aug21 prediction:
1. 130 to 150 local cases
2. 30 to 40 bolink
3. 3 to 5 new clusters
4. 2 daeths by midnight

Singapore Confirms 155 New Covid-19 Cases On 30 Aug​

The Ministry of Health (MOH) has made early confirmation of 155 new Covid-19 cases today (30 Aug).

Among them are:
  • 147 locally transmitted cases
  • 8 imported cases
Of the 147 local infections, 52 are unlinked. This is the highest number of locally transmitted cases reported in a day since 22 Jul, which saw 162 community cases that day
 
I haven’t checked for the last 2 days- I guess it’s like the Schrondinger’s cat at this point in time :biggrin::biggrin::biggrin:
u better stay at home. u no vax yet ah. no pt taking risk going out. i suspect there's far more transmission than what is tested. people nowadays don't see doc already. got symptoms also just walk around everywhere like nothing.
 


Abstract​

Not all persons recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop SARS-CoV-2–specific antibodies. We show that nonseroconversion is associated with younger age and higher reverse transcription PCR cycle threshold values and identify SARS-CoV-2 viral loads in the nasopharynx as a major correlate of the systemic antibody response.
 
another late moh prelim update means bad numbers

31aug21 prediction:

1. 150 to 170 local cases
2. 50 to 79 bolink
3. 4 to 6 new clusters
4. 2 deaths by midnight
 

BUGIS JUNCTION AND BUS INTERCHANGE CLUSTERS GROW​

New cases were added to six of the eight active clusters involving staff at bus interchanges: 13 to Boon Lay Bus Interchange; seven to Toa Payoh Bus Interchange; two each to Jurong and Tampines bus interchanges; and one each to Bishan and Punggol bus interchanges.

There are now 276 infections linked to the eight bus interchange clusters.

Eleven new cases were identified in the Bugis Junction cluster, bringing its total to 222.

Fifteen new cases were also added to the North Coast Lodge cluster, taking its tally to 166 infections.
 
new MULAN variant

GENEVA: The World Health Organization has said it is monitoring a new coronavirus variant known as Mu, which was first identified in Colombia in January.

Mu, known scientifically as B.1.621, has been classified as a "variant of interest", the global health body said Tuesday (Aug 31) in its weekly pandemic bulletin.

The WHO said the variant has mutations that indicate a risk of resistance to vaccines and stressed that further studies were needed to better understand it.
Related:

"The Mu variant has a constellation of mutations that indicate potential properties of immune escape," the bulletin said.

There is widespread concern over the emergence of new virus mutations as infection rates are ticking up globally again, with the highly transmissible Delta variant taking hold - especially among the unvaccinated - and in regions where anti-virus measures have been relaxed.

All viruses, including SARS-CoV-2 that causes COVID-19, mutate over time and most mutations have little or no effect on the properties of the virus.

But certain mutations can impact the properties of a virus and influence how easily it spreads, the severity of the disease it causes, and its resistance to vaccines, drugs and other countermeasures.

https://www.channelnewsasia.com/world/covid...itoring-2148471
 
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