丢！死啦！Hong Kong 1st hit! H1N1 Influenza

[swine_flu_H1H1]

丢！死啦！Hong Kong 1st hit! H1N1 Influenza CONFIRMED

http://tw.news.yahoo.com/article/url/d/a/090501/8/1is8c.html


香港淪陷！　1在港墨西哥人確診H1N1
TVBS 更新日期:"2009/05/01 22:37" 尤美心

香港確定出現首宗H1N1新型流感確診病例，這代表亞洲也淪陷了；在香港被確診為HIN1新型流感病例的是一位墨西哥人，目前病患已經被移往香港瑪嘉烈醫院隔離治療；香港隨即啟動「緊急」防疫措施；另外，該確診病患和他的2名墨西哥友人，以及一名曾到飯店探望他的香港人，被送往瑪嘉烈醫院隔離；這名確診病例到港居住的飯店-灣仔維景酒店，也在今晚8點，被香港警方封鎖管制；飯店內200多名房客與100多名員工，都被管制在飯店裡。

香港特首曾蔭權：「香港已經出現第一宗人類『豬流感』個案，是一個墨西哥人，昨天搭乘東方航空MU505航班，大約在下午，由墨西哥經上海到香港。」

晚間8點40分，香港特首曾蔭權親自主持這臨時記者會；從他口中說出了香港出現H1N1確診病例，証實香港淪陷為HI1N1新型流感疫區。

曾蔭權：「在這情況之下，我們聽從衛生署長的建議，將流感的級別，級數由『嚴重』提升到『緊急』！」

香港隨即啟動級別為「緊急」的防疫機制；這名確診病例，為一名墨西哥人，30日晚間，港府接獲此名墨西哥人與他的2名同伴為疑似個案，隨即展開檢驗；1日下午，這3名墨西哥人更被送往瑪嘉烈醫院，而原訂4點半要舉行的港府說明會隨之取消。記者：「曾先生，是否有確診個案？」曾蔭權：「...。」

這是下午香港媒體追問緊急開會的港府官員的畫面，不尋常的氣氛漫延；果然晚間，香港特首曾蔭權親上火線，証實出現了一起確定病例。

而香港警方隨即封鎖了確定病例墨西哥人居住的飯店「灣仔維景酒店」，而在曾蔭權對外宣佈的同時，啟動香港的緊急防疫機制，並且呼籲香港民眾，防疫不要驚慌。


<hr>

http://hk.news.yahoo.com/article/090501/4/byw5.html


本港確診首宗北美流感
(明報)5月1日 星期五 23:40

特首曾蔭權 宣布，本港確診首宗甲型流感H1N1個案，患者來自墨西哥，本港流感應變由嚴重升至緊急級別。

曾蔭權表示，該名患者昨日乘搭東航MU505班機，由墨西哥到上海 ，再轉飛至本港。他昨日抵港後出現發燒病症，到律敦治醫院 求診。衛生署 今日下午證實他為甲型流感H1N1(北美流感，前稱豬流感)疑似個案，港大醫學院晚上證實他為確診個案，現時他在律敦治醫院接受隔離治療。

曾蔭權表示，本港流感應變級別，由嚴重提升至緊急，衛生署長行使權力，將該名患者曾入住的維景酒店隔離。他呼籲市民毋須恐慌，本港其他活動，如上學及商業可如常進行，但要提高防範措施。

本港的確診個案是亞洲首宗的確診病例，另外韓國 及泰國 就有疑似個案，正待確定。

（即時新聞）

 

[swine_flu_H1H1]

Re: 丢！死啦！Hong Kong 1st hit! H1N1 Influenza CONFIRMED

http://www.recombinomics.com/News/01140901/H274Y_Korea_Explodes_More.html


Audio: Jan28 Apr21 Sep22 RSS Feed News Now

Commentary

Explosion of H1N1 Tamiflu Resistance in Korea Continues
Recombinomics Commentary 14:05
January 14, 2009
week 49 34/39 2.3%
week 50 82/95 48 3.6%
week 51 296/322 214 8.4%
week 52 767/815 471 15.39%
week 53 1275/1333 508 17.63%

The above data from the Korean CDC demonstrate the continued explosion of H1N1 Tamiflu resistance in Korea, which parallels the dramatic increase in reports of influenza like illness (ILI).

The baseline for the ILI rate is 2.6% and last season the rate peaked below 10% in week 9. This season, after crossing the baseline level in week 50, the rate jumped to 8.4% in week 51, which then jumped to 15.39% for week 52, and the latest report has the rate at 17.63%. The vast majority of influenza isolates have been H1N1. The week over week increase in H1N1 confirmations of 508 for week 52 is higher than the increase of 471 in week 53.

In the report released Friday, 16/17 H1N1 isolates were oseltamivir resistant, indicating that the vast majority of H1N1 reported in the past few weeks also has H274Y, as has been reported for neighboring Japan, as well as North America and Europe.

The explosion of H1N1 cases in Korea, in association with the fixing of H274Y is cause for concern. The sequence data from Japan and the United States identifies three receptor binding domain changes, G189V, A193T, H196R, which is likely associated with the rapid spread as well as the escape from prior immunity. None of these three changes is represented in the current H1N1 vaccine and the increased reservoir of H274Y in seasonal flu raises concerns of recombination between the N1 on H1N1 and the N1 of H5N1 to produce Tamiflu resistant H5N1. Both Korea and Japan had H5N1 in the spring of 2008, and one culler in Korea was H5 PCR confirmed.

The explosion of H1N1 in Korea may lead to similar increases in Japan and the United States. One flu outbreak has been reported at a Texas high school in the United States, where all reported influenza A has been H1N1 with H274Y.

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