Trump and hydroxychloroquine

[syed putra]

Trump touts hydroxychloroquine even as U.S. revokes emergency use status

• WORLD
• Tuesday, 16 Jun 2020
  4:06 AM MYT
• • 
    

U.S. President Donald Trump listens during a roundtable discussion on "America's seniors" in the Cabinet Room at the White House in Washington, U.S., June 15, 2020. REUTERS/Leah Millis

WHO, CDC says it does not work.
Jiu hu still uses it during early stages and

Antimalarial Drug Helped Stop Covid-19 Patients From Worsening: DG
By CodeBlue
A whopping 88% of Malaysia’s coronavirus cases are in the first two early stages.

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• 5
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Health director-general Dr Noor Hisham Abdullah. Picture from Facebook @kementeriankesihatanmalaysia.
KUALA LUMPUR, April 7 — Antimalarial medicine hydroxychloroquine may have helped prevent early Covid-19 patients from deteriorating into conditions that require intensive care or ventilator support, health authorities said.
Health director-general Dr Noor Hisham Abdullah said the Ministry of Health (MOH) has been using hydroxychloroquine, which has anti-inflammatory properties, since the coronavirus outbreak began in Malaysia.
“We monitor the side effects, but the impact we see is on Categories 1 and 2, when they did not deteriorate into Categories 4 and 5,” Dr Noor HIsham told a press conference.
“So, we feel that the medicine can help in terms of inflammation. So, fewer of our patients now enter ICU (intensive care unit) or need ventilator support. If you look now, only 5 per cent enter ICU, compared to 10 per cent in other countries.”
About 30 per cent of Covid-19 patients under ICU in Malaysia have recovered, he said, while 6.2 per cent of ICU patients succumb to coronavirus.
According to the DG, the first stage of Covid-19 is testing positive without symptoms; the second stage shows mild symptoms; the third stage has pneumonia, but doesn’t need oxygen; the fourth stage has pneumonia and needs oxygen; while the fifth stage needs ventilator support.
A whopping 88 per cent of Malaysia’s coronavirus cases are in the first two early stages, 7 per cent in the third stage, and 5 per cent in the two most severe stages. Malaysia has confirmed nearly 4,000 Covid-19 cases to date, including 63 fatalities.
Malaysia has joined the World Health Organization’s (WHO) global Solidarity Trial to test four treatment protocols for Covid-19 using different combinations of remdesivir, lopinavir/ritonavir, interferon beta, chloroquine and hydroxychloroquine.

Is this a case of Big Pharma trying to block cheap and available use of the drug?

 

[Confuseous]

Trump is spraying pepper balls all over the place to try and confuse the electorate.
His grave-like numbers explain why.

https://abacusdata.ca/biden_trump_2020_abacus-data/

 

[syed putra]

Trumps opinion is backed up by Malaysia.

 

[redbull313]

Trumps opinion is backed up by Malaysia.

then must be true

 

[Leongsam]

This shows that Trump is the best!

 

[redbull313]

Trump is best we love Trump

 

[Confuseous]

https://edition.cnn.com/2020/06/15/politics/fda-hydroxychloroquine-coronavirus/index.html

 

[jw5]

The reason why Trump took hydroxychloroquine is the same reason why he recommended it so highly several weeks ago: He has a lot of stock in his warehouse.

 

[steffychun]

Why Pinky dare not try it?

 

[Peiweh]

Trump is an entertainer people need to remember that. What a guy! who else can do this? Come one, am I right?

 

[nightsafari]

This shows that Trump is the best!

or Malaysia is the best!

 

[Confuseous]

or Malaysia is the best!

Depends. Malaysian health minister said on national TV that drinking hot water will
get rid the virus. So, they are second best, but safer, from my point of view.

 

[frenchbriefs]

The fact a senile old bat suffering from Parkinson's is beating him speaks volume......

Maybe we should give trump a second term to see how much further us can sink.

 

[shockshiok]

The fact a senile old bat suffering from Parkinson's is beating him speaks volume......

Maybe we should give trump a second term to see how much further us can sink.

us is best china is shit

 

[glockman]

I never doubted Mr Trump when he said hydroxychloroquine was effective and that he was taking it. He is a brilliant man, a world class businessman and the greatest President in the world.

 

[Hypocrite-The]

Steroid dexamethasone first drug shown to save lives of severest COVID-19 cases
A pharmacist displays a box of Dexamethasone at the Erasme Hospital amid the coronavirus disease (C
A pharmacist displays a box of Dexamethasone at the Erasme Hospital amid the coronavirus disease (COVID-19) outbreak, in Brussels, Belgium, June 16, 2020. REUTERS/Yves Herman
16 Jun 2020 11:47PM
(Updated: 17 Jun 2020 07:02AM)
Bookmark
LONDON: The steroid dexamethasone was shown on Tuesday (Jun 16) to be the first drug to significantly reduce the risk of death among severe COVID-19 cases, in trial results hailed as a "major breakthrough" in the fight against the disease.

Researchers led by a team from the University of Oxford administered the widely available drug to more than 2,000 severely ill COVID-19 patients.

Among those who could only breathe with the help of a ventilator, dexamethasone reduced deaths by one third, and by one-fifth in other patients receiving oxygen only, according to preliminary results.

Normally used to treat a range of allergic reactions as well as rheumatoid arthritis and asthma, dexamethasone is an anti-inflammatory.

Daily doses of the steroid could prevent one-in-eight ventilated patient deaths and save one out of every 25 patients requiring oxygen alone, the team said.

The trial, carried out by the RECOVERY research group that is searching for effective COVID-19 treatments, included a control group of 4,000 patients who did not receive the drug.

"Dexamethasone is the first drug to be shown to improve survival in COVID-19. This is an extremely welcome result," said Peter Horby, professor of Emerging Infectious Diseases in the Nuffield Department of Medicine, University of Oxford.

"Dexamethasone is inexpensive, on the shelf, and can be used immediately to save lives worldwide."

Britain's Health Secretary Matt Hancock said the country's patients would start to receive the drug immediately.

Hancock said the government had started stockpiling dexamethasone back in March after preliminary trials showed "early signs" of the drug's potential.

'REMARKABLE' POTENTIAL

The trial results are particularly promising as around 40 per cent of COVID-19 patients who require a ventilator end up dying, often because of the body's uncontrolled inflammatory response to the virus.

For those receiving the new treatment, the mortality rate dropped to less than 30 per cent.

"This is a major breakthrough: dexamethasone is the first and only drug that has made a significant difference to patient mortality for COVID-19," said Nick Cammack, COVID-19 therapeutics accelerator lead at the Wellcome Trust health charity.

"Potentially preventing one death in every eight ventilated patients would be remarkable."

The trial showed dexamethasone to be ineffective in treating patients with milder forms of COVID-19, however.

A number of existing drugs have been trialled as a treatment against the novel coronavirus, with mixed results.

Trials of treatment of the anti-arthritis drug hydroxychloroquine were halted in several countries after a major study in The Lancet medical journal suggested it showed no benefit among COVID-19 patients and even increased the risk of death.

That study has since been retracted due to inconsistencies in the data, but others have come to the same conclusion.

Remdesivir, an anti-viral that appears to reduce the length of treatment in some patients, is already being used in Britain, but one study in April showed it had "no significant clinical benefit".

The fact that an existing, cheap and largely side-effect free medication has been shown to be effective in severe COVID-19 cases is "of tremendous importance", according to Stephen Griffin, associate professor in the School of Medicine, University of Leeds.

"There is (now) realistic scope for further improving the clinical management of this devastating disease," said Griffin, who was not involved in the study.

Cammack said that in light of the study results, dexamethasone "must now be rolled out and accessed by thousands of critically ill patients around the world."

 

[Hypocrite-The]

Why a 'cheap, old and boring' drug is the best hope we've had for a coronavirus treatment
Two medicine bottles that read dexamethasone sit on the bend of a pharmacy
Preliminary results indicate dexamethasone could help treat severely ill patients in hospital with COVID-19. But it's early days yet.(Supplied)
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First, we tried the antimalarial drug hydroxychloroquine. Then we tested the antiviral drug remdesivir. But new UK research gives the strongest indication yet we may have found a useful treatment for COVID-19.

This time it's an old anti-inflammatory drug, dexamethasone, which has been described as cheap, old and boring.

Preliminary results from a clinical trial just released indicate the drug seems to reduce your chance of dying from COVID-19 if you're in hospital and need oxygen or a machine to help you breathe.

The results were significant enough for the UK to recommend its use for severe COVID-19.

Before we roll it out in Australia, we need to balance the drug's risks with its benefits after peer review of the full trial data.

What is dexamethasone?
Dexamethasone has been used since the late 1950s, so doctors are familiar with it. It's also inexpensive, with a packet of 30 tablets costing around $22 (for general patients) under Australia's Pharmaceutical Benefits Scheme.

So if it does work for COVID-19, this cheap and boring drug, already available in Australia with a prescription, would be easy to add to current treatments.

Dexamethasone belongs to a class of drugs known as corticosteroids and is used to treat a range of conditions related to inflammation. These include severe allergies, some types of nausea and vomiting, arthritis, swelling of the brain and spinal cord, severe asthma and for breathing difficulties in newborn babies.

And it's dexamethasone's application to those latter two respiratory conditions that prompted doctors to think it may also help patients severely affected by COVID-19.

What did the trial find?
The recently reported results come from the Randomised Evaluation of COVID-19 Therapy, or RECOVERY, trial.

The researchers put patients into one of three groups: those needing ventilation (a machine that helps them breath); those who just needed oxygen therapy; and those who needed no treatment to help them breathe.

Patients in each of those groups were given dexamethasone (6mg once a day, either as a tablet or via intravenous injection), for ten days. A fourth group (a control group) was not given the drug.

Dexamethasone was most useful for the ventilated patients; deaths for this group dropped by about one-third with drug treatment. In contrast, deaths only dropped by one-fifth for those patients who were only receiving oxygen therapy. There was no benefit to patients who could breathe normally.


Youtube Dexamethasone Is Widely Available, Inexpensive to Treat Covid-19: U.K. Scientists
The researchers calculated that giving dexamethasone to eight ventilated patients would prevent one from dying, on average. And giving it to around 25 patients needing oxygen alone would prevent one death.

How might dexamethasone work for COVID-19?
When a patient has severe COVID-19, their immune system ramps up to catch and control the virus in the lungs.

In doing this, their body produces more infection-fighting white blood cells. This results in inflammation and pressure on their lungs, making it very difficult for them to breath.

It's therefore likely dexamethasone reduces this inflammation, and so reduces pressure on the lungs.

What are the downsides?
There are potential complications with using dexamethasone.

First, dexamethasone also suppresses the immune system when it reduces inflammation. So, it's not usually recommended for people who are sick, or could be sick, from other infections. So doctors will need to make sure patients have no other infections before they are prescribed the drug.

If the results of this trial are correct though, the drug doesn't appear to compromise the patient's ability to fight COVID-19; it might just affect their ability to fight off other diseases.

Second, the drug is only useful for patients with difficulty breathing and needing some assistance either through ventilation in a hospital or from oxygen therapy.

There appears to be no benefit for patients who don't need help breathing. So we shouldn't be giving it to everyone who tests positive to the virus.

Third, like all drugs, dexamethasone has side effects that need to be monitored. Serious, but rare ones include: severe stomach or intestinal pain, sudden changes with vision, fits, significant psychiatric or personality changes, severe dizziness, fainting, weakness and chest pain or irregular heartbeat, and swelling of the face, lips, mouth, tongue or throat, which may cause difficulty in swallowing or breathing.

What happens next?
The results of the clinical trial are preliminary.

So we need to wait for the full study data and scientific peer review before we can make a definitive decision as to whether dexamethasone treatment is a worthwhile, and safe, addition to COVID-19 therapy in Australia.

Nial Wheate is associate professor and program director undergraduate pharmacy at University of Sydney. This article originally appeared on The Conversation.

 

[tobelightlight]

Trump will get a second term. Confirm with a heavy chop.

 

[Nice-Gook]

when I was in Cambodia during the United Nations take over of the country to rebuild it ..the biggest problem was mosquitoes in the rural areas ....where such mosquitoes bite you can bleed through your skin ...the army doctor, a German than prescribed Dexamethasone with a small size of Doxycycline as a precautionary measure when you entered mosquito infested territory...such medication not to be taken more than 5 days

 

[Hypocrite-The]

https://www.bitchute.com/video/Brcm2OtyDVlO/