Johor has nothing much to offer other than cheap and plentiful land and also plentiful of low skilled workers.
While some people are too ambitious had wanted so much to shed the "Singapore backyard" image off Johor, unfortunately this image will never go away and actually should stay for good.
Already some smarter and worried developers are switching to light industrial development now when facing a severe housing glut for the next five to ten years caused by extremely "poor and uncoordinated planning" as admitted by their own politicians.
Johor is actually the most desirable location for the SMEs who are not big enough to go international while the cost of doing business id too high in SG and better still, only a short drive away. While Johor is not suited for high end sophisticated engineering, research type of industry due to lack of skilled workers hence light industry like logistic, food manufacturing, domestic furniture fabrication, building components fabrication, agricultural industries like veggies/eggs/chicken/fish farming etc are most suitable.