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New COVID-19 variant spreads rapidly but poses low risk
By Adrian ChandranApril 2, 2025 @ 4:45pm

A new variant of the SARS-CoV-2 virus is on the rise in Australia, becoming New South Wales' third most dominant strain.
LP.8.1, a descendant of Omicron and JN.1, was first detected in July 2024. The World Health Organization (WHO) designated it as a variant under monitoring in January due to its rapid global spread and genetic makeup, which may enhance transmission and pose a greater health risk.

According to an SBS News report, LP.8.1 has six mutations in its spike protein - the structure that allows SARS-CoV-2 to attach to human cells. One mutation, V445R, is believed to increase the variant's ability to spread. Laboratory studies indicate that V445R enhances binding to human lung cells.
Studies suggest LP.8.1 is not more severe than other circulating strains. WHO has classified it as a variant under monitoring, stating it poses a low risk to public health and does not yet meet the criteria for a variant of interest or concern.
Current COVID-19 vaccines are expected to provide protection against LP.8.1. However, WHO member countries will continue studying its behaviour, including any potential for immune evasion.
While there is no cause for panic, continued vigilance and vaccination - especially for medically vulnerable groups - remain essential to minimising the disease's impact.