respected microbiologist and biosafety advocate Richard Ebright, PhD, continue to highlight circumstantial evidence suggesting that SARS-CoV-2 escaped from a biohazard laboratory in Wuhan, China. Such an escape might have occurred via accidental infection of a lab worker who came into contact with the isolated virus, an infected lab animal, or animal waste.
For now, we cannot definitively rule out either origin story—a lab accident or a natural animal-to-human transmission. Determining the origins of this pandemic is unlikely to help current efforts to treat and cure the disease. It could, however, be an important determinant for efforts to prevent future outbreaks.
Escape from a lab?
Most arguments in favor of the lab accident theory are based on geography. Wuhan, the site of COVID-19’s first reported cases in late 2019, is also home to two of China’s most advanced biological laboratories. The Wuhan Institute of Virology (WIV) has come under special scrutiny because it hosts China’s only biosafety level 4 lab facilities.
Ebright, a former Howard Hughes Medical Institute investigator and current laboratory director at Rutgers University, is the most prominent scientist espousing the possibility of a lab escape. He
raised biosafety concerns about WIV when it opened in 2017, as did Tim Trevan, founder of CHROME Biosafety and Biosecurity Consulting. Ebright has long opposed the expansion of preventative research into dangerous pathogens, and he views the possible lab escape of SARS-CoV-2 as strong support for that position.