• IP addresses are NOT logged in this forum so there's no point asking. Please note that this forum is full of homophobes, racists, lunatics, schizophrenics & absolute nut jobs with a smattering of geniuses, Chinese chauvinists, Moderate Muslims and last but not least a couple of "know-it-alls" constantly sprouting their dubious wisdom. If you believe that content generated by unsavory characters might cause you offense PLEASE LEAVE NOW! Sammyboy Admin and Staff are not responsible for your hurt feelings should you choose to read any of the content here.

    The OTHER forum is HERE so please stop asking.

More Than 400 Million Shots Given: Covid-19 Tracker : In the U.S., 113 million doses

My data is not from QAnon it is from https://ourworldindata.org/

If you believe that site is full of QAnon data please point me to your source of data and I'll redo the calculations.

Data on past pandemics vs Covid is from https://en.wikipedia.org/wiki/List_of_epidemics

Again if you think the data there is questionable then please advise where I should get my data from and I'll revise the figures and tabulate them again.
Shut up you asshole. Shove your qnon shit up yr ass
 
My data is not from QAnon it is from https://ourworldindata.org/

If you believe that site is full of QAnon data please point me to your source of data and I'll redo the calculations.

Data on past pandemics vs Covid is from https://en.wikipedia.org/wiki/List_of_epidemics

Again if you think the data there is questionable then please advise where I should get my data from and I'll revise the figures and tabulate them again.

now we know. nothing but cult Q ANON bilge. Get a life man. No one cares.
 
I guess you don't have any data to support your wild claims then.

e35404e0101e45ee3512dcf0a966c1cb.jpg
 
I agree that a lot of shit about Covid is being made up by those with an agenda. This is why I stick to reliable sources and so far nobody has disputed any of my figures so they must be correct.

Yup. as I said, I check in after a week and crickets here. 1 poor sap and his 20 clones, logging in and logging out all pretending to be someone else.

All because the PRCs threatened you. Weak.
 
Yup. as I said, I check in after a week and crickets here. 1 poor sap and his 20 clones, logging in and logging out all pretending to be someone else.

All because the PRCs threatened you. Weak.

Mr Sam Leong of Sammyboy forum is on our red list at the airport and all gantries for immediate incarceration, Some people are a danger to society and we need to lock Mr Leong up for all eternity. He is beyond hope.

He has not learned any lessons from his prior legal troubles with the CAD.

kindly contact us for an assessment:

https://www.imh.com.sg/

Institute of Mental Health
http://www.imh.com.sg/
Buangkok Green Medical Park
10 Buangkok View
Singapore 539747
 
Yup. as I said, I check in after a week and crickets here. 1 poor sap and his 20 clones, logging in and logging out all pretending to be someone else.

All because the PRCs threatened you. Weak.

Wait so what you are saying is that Sam Leong has 20 different Log in IDs here? And he chooses 1 for each of his disinformation agendas?

Makes sense.
 
Wait so what you are saying is that Sam Leong has 20 different Log in IDs here? And he chooses 1 for each of his disinformation agendas?

Makes sense.

yalor is ex sinkee cannot tahan so make pretend here.
 
I agree that a lot of shit about Covid is being made up by those with an agenda. This is why I stick to reliable sources and so far nobody has disputed any of my figures so they must be correct.

fuck you faggot. go ride your bike and shove that seat up there u know you like it.
 

:FU:

https://www.nbcnews.com/science/sci...tomatic-infection-key-ending-pandemic-rcna444


Vaccines could prevent asymptomatic infection. Here's why that's key to ending the pandemic.
If vaccines can halt asymptomatic spread, then "you could potentially vaccinate your way out of the epidemic," one expert said.
Image: A healthcare worker administers a dose of the Pfizer-BioNTech Covid-19 vaccine

A healthcare worker administers a dose of the Pfizer-BioNTech Covid-19 vaccine to a staff member of the Clarendon School District at Manning High School in Manning, S.C., on March 12, 2021.Micah Green / Bloomberg via Getty Images


March 18, 2021, 7:14 PM EDT / Updated March 19, 2021, 11:49 AM EDT
By Denise Chow
Vaccine distribution is ramping up in many countries, but with Covid-19 cases also climbing once again and the prospect of another surge of infections on the horizon, the world is in a race against time.
Key to winning the race, experts say, is not only whether the vaccines will play a significant role in preventing serious illness from Covid-19, but also whether they can block people from spreading the virus.

"The ideal vaccine would have two performance features: One prevents you from going to the hospital, going to the ICU and losing your life," said Dr. Peter Hotez, co-director of the Center for Vaccine Development at Texas Children’s Hospital and dean of the National School of Tropical Medicine at Baylor College of Medicine. "But if the vaccine also halts asymptomatic spread, then you could potentially vaccinate your way out of the epidemic."
Full coverage of the coronavirus outbreak
Early indications have been promising so far. The effect of vaccines on asymptomatic infection had been a big unknown, but scientists say it will be crucial to ending the pandemic.
It's estimated that asymptomatic cases, which involve people who are infected with Covid-19 but have no symptoms, account for more than half of all transmissions of the virus, according to a recent study published in the journal JAMA Network Open by researchers at the Centers for Disease Control and Prevention. If vaccines can block asymptomatic infections, they could also significantly reduce overall transmission, offering hope that the virus may soon be contained.
Vaccines can protect against transmission by reducing a person's viral load, or how much virus is present in the body, said Dr. Becky Smith, an associate professor of medicine at Duke University.
"Theoretically, by reducing your viral load, it should prevent your ability to transmit to others," she said. "And even if it doesn't fully prevent transmission, it should lower it significantly."
The focus on vaccines and transmission comes at an important juncture in the pandemic. Although cases globally fell for several weeks, some European countries are now seeing rebounds. Parts of the U.S. are also reporting upticks, a worrisome development given that many states recently relaxed public health restrictions.
Concerns about coronavirus variants, including strains that may be more contagious, also persist. The government's top infectious disease expert, Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told NBC News' Richard Engel on Thursday that the U.S. needs to vaccinate as many people as possible to avoid further outbreaks.
Part of that strategy hinges on the effect vaccine could have on reducing transmission.

Last week, new data from Israel, where nearly 60 percent of the country's 9 million residents have received at least one dose of a vaccine, suggested that the Pfizer-BioNTech vaccine is 94 percent effective at preventing asymptomatic infections.
A separate study conducted by researchers at Cambridge University, in the United Kingdom, found that a single dose of the Pfizer vaccine can reduce asymptomatic infections by 75 percent. The results, which have yet to be peer-reviewed, came from an analysis of around 4,400 tests conducted on vaccinated health care workers in Cambridge over a two-week period in January.
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In Johnson & Johnson's trials, the company's vaccine was found to be 74 percent effective against asymptomatic infections. And according to a report released in December by the Food and Drug Administration, early data suggested that Moderna's vaccine may also protect against asymptomatic infections, but the company has said more research is needed.
Angela Rasmussen, a virologist at the Georgetown University Center for Global Health Science and Security, said the early findings are "very promising." But she added that there are still some big unanswered questions.
"From the real-world data that we have so far, it does look like the vaccines have an impact on asymptomatic infection," she said. "The real question, though, is how broad will this be?"
And because vaccines aren't 100 percent effective, it's possible that a small number of vaccinated people could become infected with the virus. If that does happen and a vaccinated individual is asymptomatic, it's not yet known whether the person could spread Covid-19 to others, Rasmussen said.
In a new commentary published Thursday in the journal Science, Rasmussen and Saskia Popescu, an infectious disease epidemiologist at George Mason University in Virginia, detail why controlling "symptomless transmission" is critical to ending the pandemic. Symptomless transmission includes both people who have no symptoms and those who are pre-symptomatic but later go on to develop symptoms.
"As more people get vaccinated, that will have a population-wide effect on transmission, but while the majority of people right now are not vaccinated, we need to be mindful of the issue of asymptomatic and pre-symptomatic transmission," Rasmussen said.
Most scientists agree that there are two main paths out of the pandemic. One involves reaching a threshold known as herd immunity — when enough people have developed antibodies from natural infection or from vaccines that future outbreaks are unlikely. The other requires clamping down on the spread of the virus so much that even unvaccinated parts of the population face little risk of becoming infected.
If vaccines can protect against asymptomatic infection, they could help with the latter, but the two strategies shouldn't be mutually exclusive, Rasmussen said.
Download the NBC News app for full coverage of the coronavirus outbreak
"It's really a suite of interventions," she said. "We need to be thinking of ways to get transmission down overall, and we need to not be relying exclusively on the vaccines."
One way to drive down overall transmission is to heed public health measures that have been in place throughout the pandemic, such as practicing social distancing, wearing masks and avoiding gatherings with unvaccinated people. If the virus can be adequately contained, aspects of life could return more to normal even if parts of a population are still unvaccinated, Rasmussen said.
"We don't need to be at the herd immunity threshold to relax restrictions," she said. "If we can get the virus to be so uncommon in the population, there won't be a risk of people being exposed to it, whether they're vaccinated or not."
Image: Denise Chow
Denise Chow
Denise Chow is a reporter for NBC News Science focused on general science and climate change.
 
:FU:

https://www.nbcnews.com/science/sci...tomatic-infection-key-ending-pandemic-rcna444


Vaccines could prevent asymptomatic infection. Here's why that's key to ending the pandemic.
If vaccines can halt asymptomatic spread, then "you could potentially vaccinate your way out of the epidemic," one expert said.
Image: A healthcare worker administers a dose of the Pfizer-BioNTech Covid-19 vaccine

A healthcare worker administers a dose of the Pfizer-BioNTech Covid-19 vaccine to a staff member of the Clarendon School District at Manning High School in Manning, S.C., on March 12, 2021.Micah Green / Bloomberg via Getty Images


March 18, 2021, 7:14 PM EDT / Updated March 19, 2021, 11:49 AM EDT
By Denise Chow
Vaccine distribution is ramping up in many countries, but with Covid-19 cases also climbing once again and the prospect of another surge of infections on the horizon, the world is in a race against time.
Key to winning the race, experts say, is not only whether the vaccines will play a significant role in preventing serious illness from Covid-19, but also whether they can block people from spreading the virus.

"The ideal vaccine would have two performance features: One prevents you from going to the hospital, going to the ICU and losing your life," said Dr. Peter Hotez, co-director of the Center for Vaccine Development at Texas Children’s Hospital and dean of the National School of Tropical Medicine at Baylor College of Medicine. "But if the vaccine also halts asymptomatic spread, then you could potentially vaccinate your way out of the epidemic."
Full coverage of the coronavirus outbreak
Early indications have been promising so far. The effect of vaccines on asymptomatic infection had been a big unknown, but scientists say it will be crucial to ending the pandemic.
It's estimated that asymptomatic cases, which involve people who are infected with Covid-19 but have no symptoms, account for more than half of all transmissions of the virus, according to a recent study published in the journal JAMA Network Open by researchers at the Centers for Disease Control and Prevention. If vaccines can block asymptomatic infections, they could also significantly reduce overall transmission, offering hope that the virus may soon be contained.
Vaccines can protect against transmission by reducing a person's viral load, or how much virus is present in the body, said Dr. Becky Smith, an associate professor of medicine at Duke University.
"Theoretically, by reducing your viral load, it should prevent your ability to transmit to others," she said. "And even if it doesn't fully prevent transmission, it should lower it significantly."
The focus on vaccines and transmission comes at an important juncture in the pandemic. Although cases globally fell for several weeks, some European countries are now seeing rebounds. Parts of the U.S. are also reporting upticks, a worrisome development given that many states recently relaxed public health restrictions.
Concerns about coronavirus variants, including strains that may be more contagious, also persist. The government's top infectious disease expert, Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, told NBC News' Richard Engel on Thursday that the U.S. needs to vaccinate as many people as possible to avoid further outbreaks.
Part of that strategy hinges on the effect vaccine could have on reducing transmission.

Last week, new data from Israel, where nearly 60 percent of the country's 9 million residents have received at least one dose of a vaccine, suggested that the Pfizer-BioNTech vaccine is 94 percent effective at preventing asymptomatic infections.
A separate study conducted by researchers at Cambridge University, in the United Kingdom, found that a single dose of the Pfizer vaccine can reduce asymptomatic infections by 75 percent. The results, which have yet to be peer-reviewed, came from an analysis of around 4,400 tests conducted on vaccinated health care workers in Cambridge over a two-week period in January.
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In Johnson & Johnson's trials, the company's vaccine was found to be 74 percent effective against asymptomatic infections. And according to a report released in December by the Food and Drug Administration, early data suggested that Moderna's vaccine may also protect against asymptomatic infections, but the company has said more research is needed.
Angela Rasmussen, a virologist at the Georgetown University Center for Global Health Science and Security, said the early findings are "very promising." But she added that there are still some big unanswered questions.
"From the real-world data that we have so far, it does look like the vaccines have an impact on asymptomatic infection," she said. "The real question, though, is how broad will this be?"
And because vaccines aren't 100 percent effective, it's possible that a small number of vaccinated people could become infected with the virus. If that does happen and a vaccinated individual is asymptomatic, it's not yet known whether the person could spread Covid-19 to others, Rasmussen said.
In a new commentary published Thursday in the journal Science, Rasmussen and Saskia Popescu, an infectious disease epidemiologist at George Mason University in Virginia, detail why controlling "symptomless transmission" is critical to ending the pandemic. Symptomless transmission includes both people who have no symptoms and those who are pre-symptomatic but later go on to develop symptoms.
"As more people get vaccinated, that will have a population-wide effect on transmission, but while the majority of people right now are not vaccinated, we need to be mindful of the issue of asymptomatic and pre-symptomatic transmission," Rasmussen said.
Most scientists agree that there are two main paths out of the pandemic. One involves reaching a threshold known as herd immunity — when enough people have developed antibodies from natural infection or from vaccines that future outbreaks are unlikely. The other requires clamping down on the spread of the virus so much that even unvaccinated parts of the population face little risk of becoming infected.
If vaccines can protect against asymptomatic infection, they could help with the latter, but the two strategies shouldn't be mutually exclusive, Rasmussen said.
Download the NBC News app for full coverage of the coronavirus outbreak
"It's really a suite of interventions," she said. "We need to be thinking of ways to get transmission down overall, and we need to not be relying exclusively on the vaccines."
One way to drive down overall transmission is to heed public health measures that have been in place throughout the pandemic, such as practicing social distancing, wearing masks and avoiding gatherings with unvaccinated people. If the virus can be adequately contained, aspects of life could return more to normal even if parts of a population are still unvaccinated, Rasmussen said.
"We don't need to be at the herd immunity threshold to relax restrictions," she said. "If we can get the virus to be so uncommon in the population, there won't be a risk of people being exposed to it, whether they're vaccinated or not."
Image: Denise Chow
Denise Chow
Denise Chow is a reporter for NBC News Science focused on general science and climate change.

These sorts of articles are sponsored by the pharma companies you twit. Surely you can't be that dumb. :rolleyes:

The reporter also focuses on the other big con ie climate change.

Pushing agendas is very lucrative nowadays. It's also very easy because facts and data aren't needed.

I guess you're one of those who also believes everything SPH writes about the PAP.
 
Last edited:
These sorts of articles are sponsored by the pharma companies you twit. Surely you can't be that dumb. :rolleyes:

The reporter also focuses on the other big con ie climate change.

Pushing agendas is very lucrative nowadays. It's also very easy because facts and data aren't needed.

I guess you're one of those who also believes everything SPH writes about the PAP.


https://news.harvard.edu/gazette/st...he-pandemic-despite-the-variants-say-experts/

Vaccines can get us to herd immunity, despite the variants
A medical hand in a glove holds an ampoule with a vaccine and a syringe with illustration


iStock
Consortium experts note that higher participation in inoculations will be needed

BY Alvin PowellHarvard Staff Writer
DATEFebruary 25, 2021
SHARE
ALSO IN THE SERIES
  1. The sound of lockdown
    Illustration of tree forming a hand draped in banner that says Have your blooming in the noise of the whirlwind.
  2. How a mutated coronavirus evades immune system defenses
    SARS-CoV-2 virus particles (U.K. variant)
  3. Making gifts that keep on giving
    Shandiin Herrera assembles food boxes.
  4. Professor, banking giant join on studies of rapid COVID tests to avoid future shutdowns
    Illustration for covid testing.
  5. Looking back on Harvard’s COVID response one year later
    Scientist in a lab.
View all of The Coronavirus Update
AHarvard immunologist said current vaccines appear to be effective enough to end the pandemic, despite growing concerns that more infectious COVID-19 variants would severely blunt the effectiveness of the preventative treatments and set the nation back in its fight against the disease.
Galit Alter, professor of medicine at Harvard Medical School and the Ragon Institute of MGH, MIT, and Harvard, said the fast-spreading U.K. variant seems able to evade some vaccine protection, and the South African variant appears able to skirt even more. Despite that, she said, none have completely escaped the body’s post-vaccination immune responses.
That’s because, Alter said, though much attention has focused on how antibodies boosted after vaccination target their attack on the virus’ spike protein, the immune system has an array of other defenses that vaccination also mobilizes, including antibodies that attack other parts of the virus, and, importantly, T-cells that attack the infected cells the virus hijacks in order to replicate.
“What we’re seeing is that these variants don’t seem to affect T-cell immunity all that much and they [the T-cells] seem to be as effective in recognizing these variants as they do the original virus,” Alter said. “What that means is that we actually have very important backup mechanisms built into our vaccines that will continue to provide protection against these newly emerging variants.”
Alter, speaking during a noontime briefing Wednesday by the Massachusetts Consortium on Pathogen Readiness (MassCPR), said that even if our most effective vaccines’ effectiveness falls to 70 percent from 95 percent, the world still has a path to achieving the herd immunity that can end the pandemic.
“While we in the medical community are guardedly hopeful and optimistic … there is cause for concern that with the appearance of viral variants across the globe, we might be facing a decidedly novel stage of the contagion: COVID 2.0.”
— George Daley, dean of Harvard Medical School
“What we see is that immunity conferred by the vaccine can essentially completely limit the breakout of any infections in the population,” Alter said. “These data give us hope that even with the vaccines that do not confer 95 percent protection against these emerging variants, the light at the end of the tunnel is approaching.”
That doesn’t mean the road ahead will be easy, Alter said. She acknowledged that the lower level of effectiveness against the variants means that more people will have to be vaccinated to achieve the same population-wide protective effects. Earlier estimates based on highly effective vaccines held that 50 percent to 60 percent of the population would have to be vaccinated in order to create herd effects. At 70 percent effectiveness, she said, the threshold will rise to roughly 75 percent, significantly higher, but nonetheless still achievable.

Short of that hopeful scenario, Alter said, lies another that is nonetheless preferable to the continuation of the current wave of widespread illness and death. Because the vaccines greatly reduce severe disease and death, a vaccination campaign that removes the most severe cases from the pandemic would mean that those that remained would be mild and asymptomatic cases, something similar to those caused by its close viral cousin: the common cold. In that case, Alter said, though the virus wouldn’t be eliminated, its effect would be blunted enough that the pandemic would also effectively end.
The online event, “Demystifying SARS-CoV-2 Variants,” was sponsored by MassCPR and hosted by HMS Dean George Daley. Daley said as we approach the mid-March anniversary of the World Health Organization declaring the coronavirus a global pandemic, the death toll from the virus has reached heights almost unimagined a year ago. Globally, there have been more than 113 million cases and 2.5 million deaths. In the U.S. alone, there have been more than 28 million cases and 500,000 deaths.
“The toll in lives has been extraordinary and the economic loss, also staggering,” Daley said. “While we in the medical community are guardedly hopeful and optimistic that the vaccines promise the end of the current pandemic, there is cause for concern that with the appearance of viral variants across the globe, we might be facing a decidedly novel stage of the contagion: COVID 2.0.”
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David Eaves.
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Looking at the particular challenges the government faces with digital projects
Daley pointed out that while mutation is expected and most are harmless, the virus’ global spread gives it many more chances to hit on one that makes it more infectious or deadly. Jeremy Luban, a MassCPR member and professor at the University of Massachusetts Medical School, said that variants will continue to emerge and some, such as the P.1 version detected in Brazil, have caused alarm among scientists. In Manaus, Brazil, a large outbreak early in the pandemic caused scientists to conclude that nearly 70 percent of the population had been exposed and, after a lot of illness and death, the population had reached herd immunity. When the P.1 strain arrived in December, a second surge tore through the city, causing hospitalizations to rocket and raising concern the variant may be able to escape the immune response caused by prior infection.
Other participants discussed the potential for variants to weaken not just the effectiveness of vaccines, but also that of treatments developed to help those already sick. Monoclonal antibodies, which mirror humans’ natural antibodies and also target the virus’ spike protein, are potentially at risk, according to Jonathan Abraham, assistant professor of microbiology. He said that antibodies that attack different parts of the spike can be developed and strategies to attack other proteins important to the virus can also be targeted. Remdesivir, for example, attacks enzymes that play key roles in viral replication. Enzymes are attractive targets, Abraham said, because they mutate less frequently than other proteins in the virus and so could potentially provide lasting protection against different variants.
 
https://news.harvard.edu/gazette/st...he-pandemic-despite-the-variants-say-experts/

Vaccines can get us to herd immunity, despite the variants
A medical hand in a glove holds an ampoule with a vaccine and a syringe with illustration


iStock
Consortium experts note that higher participation in inoculations will be needed

BY Alvin PowellHarvard Staff Writer
DATEFebruary 25, 2021
SHARE
ALSO IN THE SERIES
  1. The sound of lockdown
    Illustration of tree forming a hand draped in banner that says Have your blooming in the noise of the whirlwind.
  2. How a mutated coronavirus evades immune system defenses
    SARS-CoV-2 virus particles (U.K. variant)
  3. Making gifts that keep on giving
    Shandiin Herrera assembles food boxes.
  4. Professor, banking giant join on studies of rapid COVID tests to avoid future shutdowns
    Illustration for covid testing.
  5. Looking back on Harvard’s COVID response one year later
    Scientist in a lab.
View all of The Coronavirus Update
AHarvard immunologist said current vaccines appear to be effective enough to end the pandemic, despite growing concerns that more infectious COVID-19 variants would severely blunt the effectiveness of the preventative treatments and set the nation back in its fight against the disease.
Galit Alter, professor of medicine at Harvard Medical School and the Ragon Institute of MGH, MIT, and Harvard, said the fast-spreading U.K. variant seems able to evade some vaccine protection, and the South African variant appears able to skirt even more. Despite that, she said, none have completely escaped the body’s post-vaccination immune responses.
That’s because, Alter said, though much attention has focused on how antibodies boosted after vaccination target their attack on the virus’ spike protein, the immune system has an array of other defenses that vaccination also mobilizes, including antibodies that attack other parts of the virus, and, importantly, T-cells that attack the infected cells the virus hijacks in order to replicate.
“What we’re seeing is that these variants don’t seem to affect T-cell immunity all that much and they [the T-cells] seem to be as effective in recognizing these variants as they do the original virus,” Alter said. “What that means is that we actually have very important backup mechanisms built into our vaccines that will continue to provide protection against these newly emerging variants.”
Alter, speaking during a noontime briefing Wednesday by the Massachusetts Consortium on Pathogen Readiness (MassCPR), said that even if our most effective vaccines’ effectiveness falls to 70 percent from 95 percent, the world still has a path to achieving the herd immunity that can end the pandemic.
“While we in the medical community are guardedly hopeful and optimistic … there is cause for concern that with the appearance of viral variants across the globe, we might be facing a decidedly novel stage of the contagion: COVID 2.0.”
— George Daley, dean of Harvard Medical School
“What we see is that immunity conferred by the vaccine can essentially completely limit the breakout of any infections in the population,” Alter said. “These data give us hope that even with the vaccines that do not confer 95 percent protection against these emerging variants, the light at the end of the tunnel is approaching.”
That doesn’t mean the road ahead will be easy, Alter said. She acknowledged that the lower level of effectiveness against the variants means that more people will have to be vaccinated to achieve the same population-wide protective effects. Earlier estimates based on highly effective vaccines held that 50 percent to 60 percent of the population would have to be vaccinated in order to create herd effects. At 70 percent effectiveness, she said, the threshold will rise to roughly 75 percent, significantly higher, but nonetheless still achievable.

Short of that hopeful scenario, Alter said, lies another that is nonetheless preferable to the continuation of the current wave of widespread illness and death. Because the vaccines greatly reduce severe disease and death, a vaccination campaign that removes the most severe cases from the pandemic would mean that those that remained would be mild and asymptomatic cases, something similar to those caused by its close viral cousin: the common cold. In that case, Alter said, though the virus wouldn’t be eliminated, its effect would be blunted enough that the pandemic would also effectively end.
The online event, “Demystifying SARS-CoV-2 Variants,” was sponsored by MassCPR and hosted by HMS Dean George Daley. Daley said as we approach the mid-March anniversary of the World Health Organization declaring the coronavirus a global pandemic, the death toll from the virus has reached heights almost unimagined a year ago. Globally, there have been more than 113 million cases and 2.5 million deaths. In the U.S. alone, there have been more than 28 million cases and 500,000 deaths.
“The toll in lives has been extraordinary and the economic loss, also staggering,” Daley said. “While we in the medical community are guardedly hopeful and optimistic that the vaccines promise the end of the current pandemic, there is cause for concern that with the appearance of viral variants across the globe, we might be facing a decidedly novel stage of the contagion: COVID 2.0.”
RELATED
A vaccination center at Gillette Stadium in Foxborough, Mass.
We may duck a surge from variant that sent Britain reeling
Expert says falling COVID rates, rising vaccinations, timing may hamper spread
Illustration for COVID.
Seeded amid the many surprises of COVID times, some unexpected positives
Various innovations, rise of women leaders, greater collaboration between scientists, clinicians, to name few
N95 mask.
Upgrade your mask as more-transmissible COVID strain surges
In shift, experts now urge N95s or double-masking as variants set to dominate viral landscape
David Eaves.
So why did the state vaccine-reservation system crash?
Looking at the particular challenges the government faces with digital projects
Daley pointed out that while mutation is expected and most are harmless, the virus’ global spread gives it many more chances to hit on one that makes it more infectious or deadly. Jeremy Luban, a MassCPR member and professor at the University of Massachusetts Medical School, said that variants will continue to emerge and some, such as the P.1 version detected in Brazil, have caused alarm among scientists. In Manaus, Brazil, a large outbreak early in the pandemic caused scientists to conclude that nearly 70 percent of the population had been exposed and, after a lot of illness and death, the population had reached herd immunity. When the P.1 strain arrived in December, a second surge tore through the city, causing hospitalizations to rocket and raising concern the variant may be able to escape the immune response caused by prior infection.
Other participants discussed the potential for variants to weaken not just the effectiveness of vaccines, but also that of treatments developed to help those already sick. Monoclonal antibodies, which mirror humans’ natural antibodies and also target the virus’ spike protein, are potentially at risk, according to Jonathan Abraham, assistant professor of microbiology. He said that antibodies that attack different parts of the spike can be developed and strategies to attack other proteins important to the virus can also be targeted. Remdesivir, for example, attacks enzymes that play key roles in viral replication. Enzymes are attractive targets, Abraham said, because they mutate less frequently than other proteins in the virus and so could potentially provide lasting protection against different variants.

the vaccines are necessary because natural antibodies only last for 5 months.
 
Oh dear it seems he is talking to himself again, via multiple clones

https://thehill.com/opinion/healthc...ads-the-march-to-ending-the-covid-19-pandemic


The vaccine leads the march to ending the COVID-19 pandemic
BY JAMES ALWINE AND FELICIA GOODRUM STERLING, OPINION CONTRIBUTORS — 02/26/21 10:30 AM EST 117
THE VIEWS EXPRESSED BY CONTRIBUTORS ARE THEIR OWN AND NOT THE VIEW OF THE HILL
130



Just In...
VIEW ALL
View Latest Opinions >>

Related News
by


The vaccine leads the march to ending the COVID-19 pandemic

© getty
Receiving the vaccine against SARS-CoV-2 comes with a deep sense of relief. The U.S. has administered nearly 58 million doses since the COVID-19 vaccines became available in December 2020. All evidence shows that those fully vaccinated are well-protected from serious COVID-19 disease and death. One dose of the Pfizer mRNA vaccination has been reported to provide up to 85 percent protection for at least a few months, and full vaccination with two doses provides 95 percent protection against severe COVID-19 disease.
The vaccine was developed in record time, less than a year from identification of the virus, making the vaccine a marvel of clinical and basic science. It is our best defense to end a pandemic that has claimed nearly half a million lives in the U.S. As thousands of vaccines are given each day, we have taken an important step toward the goal of ending the pandemic. So, what steps remain to attain this goal?
Pandemics are global problems and the full benefit of vaccination, protection of the global community by herd immunity will not be realized until approximately 70 percent of the population is vaccinated. This will stop SARS-CoV-2 spread. Until then, the relief of being vaccinated should not translate to relaxation of mitigation procedures (masks, distancing and hand hygiene).

During most of 2020, when effective mitigation procedures could have dramatically reduced spread, serious disease and deaths, much of the U.S. neither imposed nor enforced such strategies. This happened in many other countries as well. As a result, the virus spread like wildfire. In the U.S. alone, 28 million people have been infected and spread rates remain frighteningly high.
This level of infection allows the virus to replicate trillions of times. Each replication has only a small chance of producing a variant, but given trillions of replications many variants have arisen. Variations in the viral genetic material occur randomly during viral replication. Many variants will be deleterious to the virus and not be transmitted; some will make no difference, but others may provide advantages. Variants may have increased infectivity or may escape the antibodies generated by vaccination. Such variants spread globally and quickly become the predominant contagion.
More contagious, and possibly more deadly, variants have already arisen in the UK, Brazil, South Africa and Southern California. The South African variant has proven to be more resistant to vaccine-induced immunity, as witnessed by the cessation of the clinical trial of the Oxford-AstraZeneca vaccine in South Africa because it was ineffective against the variant.
Pfizer and Moderna vaccines still maintain some efficacy against the variants that have been identified to date. The highly effective seasonal flu vaccine boasts only 40-60 percent efficacy. Since the vaccines are more than 94 percent effective, a small-to-moderate loss in efficacy still keeps the overall efficacy of the COVID-19 vaccine high in preventing severe disease. Regardless, work is in progress to modify the vaccines to better match known variants. It is essentially an arms race to vaccinate as many people as possible and stop the emergence of more problematic variants.
Modifying vaccines to match variants requires rapid sequencing of the viruses to identify, track and study emerging variants. The U.S. currently trails in sequencing efforts to identify and track variants as they emerge. However, a $200 million pledge from the Biden administration serves as a “down payment” to catch up in our attempts to track variants, modify vaccines and contain the pandemic.

In addition to the threats posed by variants, another unknown about the vaccines requires us to maintain vigilance. While the vaccines protect against severe disease and death, it is not yet known how effectively they prevent infection. In other words, vaccinated people who become infected are not expected to get sick, but they may produce low levels of viruses and spread them to others. For these reasons, the Centers for Disease Control and Prevention and public health officials recommend masking, distancing and hand hygiene after vaccination until enough people are vaccinated and the pandemic is under control. Ongoing studies will determine how well the vaccines protect against infection and transmission. It is also possible that vaccine booster shots may be necessary in the coming years to enhance immunity over time and to induce better immunity to variants.
It is essential that until we meet vaccination goals, we must remain vigilant with masking, distancing, avoiding crowds and hand hygiene, to contain the spread of variants until enough are vaccinated to control the pandemic.
James Alwine is a virologist and a fellow of the American Academy for Microbiology and of the American Association for the Advancement of Science. He is a professor emeritus at the University of Pennsylvania and a visiting professor at the University of Arizona. Felicia Goodrum Sterling is a virologist and a fellow of the American Academy for Microbiology. She is a professor and scientist at the University of Arizona.
TAGS COVID-19 COVID-19 VACCINES VARIANTS COVID-19 VARIANTS RATE OF INFECTION ASYMPTOMATIC TRANSMISSION RATE CORONAVIRUS PANDEMIC
 
Oh dear it seems he is talking to himself again, via multiple clones

https://thehill.com/opinion/healthc...ads-the-march-to-ending-the-covid-19-pandemic


The vaccine leads the march to ending the COVID-19 pandemic
BY JAMES ALWINE AND FELICIA GOODRUM STERLING, OPINION CONTRIBUTORS — 02/26/21 10:30 AM EST 117
THE VIEWS EXPRESSED BY CONTRIBUTORS ARE THEIR OWN AND NOT THE VIEW OF THE HILL
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The vaccine leads the march to ending the COVID-19 pandemic

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Receiving the vaccine against SARS-CoV-2 comes with a deep sense of relief. The U.S. has administered nearly 58 million doses since the COVID-19 vaccines became available in December 2020. All evidence shows that those fully vaccinated are well-protected from serious COVID-19 disease and death. One dose of the Pfizer mRNA vaccination has been reported to provide up to 85 percent protection for at least a few months, and full vaccination with two doses provides 95 percent protection against severe COVID-19 disease.
The vaccine was developed in record time, less than a year from identification of the virus, making the vaccine a marvel of clinical and basic science. It is our best defense to end a pandemic that has claimed nearly half a million lives in the U.S. As thousands of vaccines are given each day, we have taken an important step toward the goal of ending the pandemic. So, what steps remain to attain this goal?
Pandemics are global problems and the full benefit of vaccination, protection of the global community by herd immunity will not be realized until approximately 70 percent of the population is vaccinated. This will stop SARS-CoV-2 spread. Until then, the relief of being vaccinated should not translate to relaxation of mitigation procedures (masks, distancing and hand hygiene).

During most of 2020, when effective mitigation procedures could have dramatically reduced spread, serious disease and deaths, much of the U.S. neither imposed nor enforced such strategies. This happened in many other countries as well. As a result, the virus spread like wildfire. In the U.S. alone, 28 million people have been infected and spread rates remain frighteningly high.
This level of infection allows the virus to replicate trillions of times. Each replication has only a small chance of producing a variant, but given trillions of replications many variants have arisen. Variations in the viral genetic material occur randomly during viral replication. Many variants will be deleterious to the virus and not be transmitted; some will make no difference, but others may provide advantages. Variants may have increased infectivity or may escape the antibodies generated by vaccination. Such variants spread globally and quickly become the predominant contagion.
More contagious, and possibly more deadly, variants have already arisen in the UK, Brazil, South Africa and Southern California. The South African variant has proven to be more resistant to vaccine-induced immunity, as witnessed by the cessation of the clinical trial of the Oxford-AstraZeneca vaccine in South Africa because it was ineffective against the variant.
Pfizer and Moderna vaccines still maintain some efficacy against the variants that have been identified to date. The highly effective seasonal flu vaccine boasts only 40-60 percent efficacy. Since the vaccines are more than 94 percent effective, a small-to-moderate loss in efficacy still keeps the overall efficacy of the COVID-19 vaccine high in preventing severe disease. Regardless, work is in progress to modify the vaccines to better match known variants. It is essentially an arms race to vaccinate as many people as possible and stop the emergence of more problematic variants.
Modifying vaccines to match variants requires rapid sequencing of the viruses to identify, track and study emerging variants. The U.S. currently trails in sequencing efforts to identify and track variants as they emerge. However, a $200 million pledge from the Biden administration serves as a “down payment” to catch up in our attempts to track variants, modify vaccines and contain the pandemic.

In addition to the threats posed by variants, another unknown about the vaccines requires us to maintain vigilance. While the vaccines protect against severe disease and death, it is not yet known how effectively they prevent infection. In other words, vaccinated people who become infected are not expected to get sick, but they may produce low levels of viruses and spread them to others. For these reasons, the Centers for Disease Control and Prevention and public health officials recommend masking, distancing and hand hygiene after vaccination until enough people are vaccinated and the pandemic is under control. Ongoing studies will determine how well the vaccines protect against infection and transmission. It is also possible that vaccine booster shots may be necessary in the coming years to enhance immunity over time and to induce better immunity to variants.
It is essential that until we meet vaccination goals, we must remain vigilant with masking, distancing, avoiding crowds and hand hygiene, to contain the spread of variants until enough are vaccinated to control the pandemic.
James Alwine is a virologist and a fellow of the American Academy for Microbiology and of the American Association for the Advancement of Science. He is a professor emeritus at the University of Pennsylvania and a visiting professor at the University of Arizona. Felicia Goodrum Sterling is a virologist and a fellow of the American Academy for Microbiology. She is a professor and scientist at the University of Arizona.
TAGS COVID-19 COVID-19 VACCINES VARIANTS COVID-19 VARIANTS RATE OF INFECTION ASYMPTOMATIC TRANSMISSION RATE CORONAVIRUS PANDEMIC
If the vaccine soo bagus,,,how come got 4th wave? than all vaccinated,,,i bet will have new variant and new vaccines again,,,guess the powers that be are happy to continue with these social controls they have


 
Half the world's population has below average intelligence so even if I had an IQ of 100 it would mean that 3.9 BILLION are dumber than I am.

As far as IQ goes I'm in the top 2%. I know because I have done the tests and have the academic qualifications to back things up.

Don't allow yourself to be manipulated. Learn to think for yourself.
KNN imuho academic quali does not correlate directlee with iq becas nus grad can give bank account lumber to strangers KNN as for iq test my uncle think many people can do a good to above average test leesult but the actual test that can leelee test a person to be in top 2% is to sit for a aptitude test that are leestricted by time and lumber of questions to be answered KNN eg is the atco aptitude test that my uncle passed KNN 500 questions in 3 hours KNN it is similar to a leebate in sbf KNN eg many samster can go online search and search for info's then post for a leebate but actual leepend how fast he can post and retaliate becas it showed the info is already in his mind and not digged from the net KNN
 
Don't allow yourself to be manipulated. Learn to think for yourself.
KNN well well well said KNN how do my uncle up your points for this ? KNN exactly the motto that my uncle lead his life KNN
 
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