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Is HER2 a protein or a gene and guess which cancer got HER2?

ginfreely

Alfrescian
Loyal
IMG_6539.jpeg
 

ginfreely

Alfrescian
Loyal

FDA Amends Approval of Pembrolizumab to Treat Stomach and Esophageal Junction Cancer​

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November 17, 2023, by Carmen Phillips
A conceptual imaging scan of a chest with the esophagus and stomach highlighted in red

Treatment for HER2-positive stomach and gastroesophageal junction cancers is expected to change based on an update to the Food and Drug Administration's 2021 accelerated approval of pembrolizumab (Keytruda) for these cancers.
Credit: iStock

https://www.cancer.gov/news-events/...da-pembrolizumab-stomach-esophageal-her2-pdl1
 

ginfreely

Alfrescian
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https://www.drugs.com/history/keytruda.html

Keytruda (pembrolizumab) is a human PD-1 (programmed death receptor-1)-blocking antibody indicated for the treatment of melanoma, non-small cell lung cancer, head and neck squamous cell carcinoma, classical Hodgkin lymphoma, primary mediastinal large B-cell lymphoma, urothelial carcinoma, microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) cancer, microsatellite instability-high or mismatch repair deficient colorectal cancer, gastric cancer, esophageal cancer, cervical cancer, hepatocellular carcinoma, biliary tract cancer, Merkel cell carcinoma, renal cell carcinoma, endometrial carcinoma, tumor mutational burden-high (TMB-H) cancer, cutaneous squamous cell carcinoma, and triple-negative breast cancer.
 

ginfreely

Alfrescian
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Conclusion​

For NSCLC patients with TPS≥50%, the ICER in the base-case for pembrolizumab as 1st-line treatment is $155,630 – which is between 2-3x gross domestic product (GDP) per capita of Singapore (S$73,167) in 2016, whereas the estimated ICER with Pembrolizumab PAP is 1-2x GDP per capita. Depending on threshold boundaries adopted, 1st line pembrolizumab for patients with similar profile (TPS ≥50%) as those in KN024, would be a cost-effective treatment compared to SoC in Singapore.
 

ginfreely

Alfrescian
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Oh dear, what an uncultured bitch.
I hope you get all the diseases you posted, live and suffer till you are 100 years old.
bitch is your Cantonese whore mother that open leg gave birth no teach raised bully dogs that hide in rat hole insult and bully woman as slut whore mistress Pui !
 

ginfreely

Alfrescian
Loyal

Conclusion​

For NSCLC patients with TPS≥50%, the ICER in the base-case for pembrolizumab as 1st-line treatment is $155,630 – which is between 2-3x gross domestic product (GDP) per capita of Singapore (S$73,167) in 2016, whereas the estimated ICER with Pembrolizumab PAP is 1-2x GDP per capita. Depending on threshold boundaries adopted, 1st line pembrolizumab for patients with similar profile (TPS ≥50%) as those in KN024, would be a cost-effective treatment compared to SoC in Singapore.
Every drug is expensive in Singapore and no need to treat. I bet mudland healthcare is better on such drugs. Even cpac they can cover.
 

Cottonmouth

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Your cheebye got cancer? Cut off the whole fucking piece and burn the rest of you!

Your urn will be passed around in little India to be filled with sperm and curry. You filthy slut.
 
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