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Concerned over high premiums of targets, the large-cap pharmaceutical companies have taken a backseat in acquisitions this year as they focused on repayment of debt accumulated due to previous deals.
Meanwhile, with the need to sustain the long-term growth, their medium size rivals have picked up the slack thanks to new sources of capital.
So far in 2021, the midcap drug companies have executed nine deals valued at $13.1B, nearly twice the amount spent by their larger rivals on eight acquisitions, The Wall Street Journal reported citing data from Evaluate Group Ltd.
“That’s a sign of their maturity, and the expanded scope of the capital markets for these companies that were previously largely shut out,” SVB Leerink analyst Geoffrey Porges points out.
Large-cap pharma companies such as AstraZeneca (NASDAQ:AZN), AbbVie (NYSE:ABBV), and Pfizer (NYSE:PFE) have dominated the deal-making over the past ten years. From 2016 to 2020, the group has splashed out $452.3B in 178 deals in comparison to $55.8B spent by mid-size players at 155 deals.
According to analysts, big pharma has taken aback this year due to a lack of targets that they think could meaningfully boost their operations. In addition, the fear of anticompetitive concerns from regulators and premiums of targets that have exceeded 65% in recent years have also contributed.
Highlighting the risks of acquisitions, Jefferies analyst David Steinberg noted: “One transaction can sink a company, particularly if it’s a very large acquisition relative to the size of the company.” According to Porges, new ways to fund transactions have helped drive the recent M&A activity.
Last month, a strategic funding partnership with Royalty Pharma (NASDAQ:RPRX) helped mid-cap biotech MorphoSys to strike an agreement to acquire Constellation Pharma (NASDAQ:CNST) for $1.7B in cash.