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Associate Professor Deborah Friedman (pictured) explained that the Buruli ulcer is a skin infection caused by the bacterium mycobacterium ulcerans - which can come from mosquito bites and possum faeces
Despite the warning, Ms Freidman believes the risk of acquiring the ulcer in these areas is low, but they have been flagged as potential areas of concern.
Areas such as Rye, Sorrento, Blairgowrie and Tootgarook are the highest risk areas of transmission, according to Victorian health chiefs.
Deborah Friedman, Victoria's deputy chief health officer for communicable disease, said that genetic analysis of the bacteria showed it came from a common source - possums.
'The potential source of M. ulcerans in Melbourne's inner north has not been established, although the bacteria were isolated from the faeces of a local possum,' Ms Friedman noted.
It's also claimed that the disease is not transmissible from person to person and there is no evidence of transmission from possums directly to humans.
The lesions usually present as a slowly developing painless nodule or papule which can initially be mistaken for an insect bite.
They can progress over weeks to a destructive skin ulcer which is known as Buruli or Bairnsdale ulcer.
Ms Friedman said 'early diagnosis is critical to prevent skin and tissue loss.'
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